© 2025 札幌心臓血管クリニック　Recruit

research achievements

-　2025　-

Robot-Assisted Minimally Invasive Strategy for a Large Mobile Thrombus Originating From the Left Atrial Appendage

Otake R, Hama G, Kasai Y, Horita R, Shitan H, Kitai T, Hachinohe D.

JACC Case Rep. 2025 Oct 29;30(34):105831. doi: 10.1016/j.jaccas.2025.105831.

Tissue Fragments From Peripheral Vasculature Entrained by Transcatheter Aortic Valve Replacement Delivery Catheter Capsule.

Otake R, Haraguchi T, Horita R, Shitan H, Hachinohe D.

JACC: CARDIOVASCULAR INTERVENTIONS 2025 July 28. doi: 10.1016/j.ijcard.2025.133427.

Validation of MitraScore in diverse mitral regurgitation subtypes: Insights from the OCEAN-mitral registry.

Nonaka H, Asami M, Horiuchi Y, Tanaka J, Gonda Y, Taniwaki M, Komiyama K, Tanabe K, Yamamoto M, Kubo S, Saji M, Izumi Y, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bota H, Ohno Y, Hachinohe D, Yamawaki M, Ueno H, Mizutani K, Otsuka T, Hayashida K; OCEAN-Mitral investigators.

Int J Cardiol. 2025 Oct 1;436:133427. doi: 10.1016/j.ijcard.2025.133427.

Prognostic value of leaflet coaptation gap in transcatheter edge-to-edge repair for functional mitral regurgitation.

Nishiura N, Kubo S, Ono S, Mushiake K, Osakada K, Maruo T, Kadota K, Yamamoto M, Saji M, Izumi Y, Asami M, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bota H, Ohno Y, Hachinohe D, Yamawaki M, Ueno H, Mizutani K, Otsuka T, Hayashida K; OCEAN-Mitral investigators.

Heart. 2025 Sep 8:heartjnl-2024-325585. doi: 10.1136/heartjnl-2024-325585.

Intravascular Ultrasound Findings Associated With Hydrodynamic Contrast Recanalization (HDR) of Coronary Chronic Total Occlusions.

Arain SA, Nascimbene A, Yarrabothula A, Hudson J, Brilakis ES, Colombo A, Azzalini L, Iqbal MB, Cortese B, Tadano Y, Fujita T, Carlino M, Kar B.

Catheter Cardiovasc Interv. 2025 Sep 2. doi: 10.1002/ccd.70094.

Real-World Outcomes of the Initial Clip Selection for Transcatheter Edge-to-Edge Repair Using the MitraClip G4 From the Optimized Catheter Valvular Intervention-Mitral Registry.

Kubo S, Yamamoto M, Saji M, Asami M, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Izumi Y, Amaki M, Kodama K, Yamaguchi J, Hachinohe D, Naganuma T, Bota H, Ohno Y, Yamawaki M, Ueno H, Nakazawa G, Otsuka T, Hayashida K; OCEAN‐Mitral investigators.

J Am Heart Assoc. 2025 Sep 2;14(17):e041907. doi: 10.1161/JAHA.125.041907.

Coronary venous occlusion by prior catheter ablation within the coronary venous system: a potential risk of precluding branch mapping and adjunctive chemical ablation.

Shirai Y, Shiohira S, Sasaki T, Kasai Y, Kitai T, Kamata T, Kawabata M, Okishige K, Sasano T, Hirao K.

J Interv Card Electrophysiol. 2025 Sep;68(6):1151-1157. doi: 10.1007/s10840-025-02107-7.

Efficacy of Direct Injection in Occlusive Lesion (DIOL) Fashion for Infrapopliteal and Inframalleolar Chronic Total Occlusions.

Haraguchi T, Fujita T, Tsujimoto M, Kasai Y, Kashima Y, Sato K.

Catheter Cardiovasc Interv. 2025 Sep;106(3):1610-1618. doi: 10.1002/ccd.31729.

Implication of the Dose of Mineralocorticoid Receptor Antagonist Following Transcatheter Edge-to-Edge Mitral Valve Repair.

Imamura T, Tanaka S, Fukuda N, Ueno H, Kinugawa K, Kubo S, Yamamoto M, Izumi Y, Saji M, Asami M, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bota H, Ohno Y, Hachinohe D, Yamawaki M, Mizutani K, Otsuka T, Hayashida K; the; OCEAN-Mitral Investigators.

JACC Asia. 2025 Sep;5(9):1095-1106. doi: 10.1016/j.jacasi.2025.03.014.

Early- Versus Newer-Generation Transcatheter Mitral Valve Edge-to-Edge Repair Systems: Insights From the OCEAN-Mitral Registry.

Okuno T, Izumo M, Kuwata S, Akashi YJ, Yamamoto M, Kubo S, Saji M, Izumi Y, Enta Y, Shirai S, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bota H, Ohno Y, Asami M, Hachinohe D, Yamawaki M, Ueno H, Mizutani K, Otsuka T, Hayashida K; OCEAN-Mitral Investigators.

JACC Asia. 2025 Sep;5(9):1110-1120. doi: 10.1016/j.jacasi.2025.05.013.

Successful Tip Detection-Antegrade Dissection and Re-Entry for Chronic Iatrogenic Coronary Artery Dissection Using a 6Fr Guiding Catheter: A Technical Challenge Overcome.

Putra BE, Kaneko U, Tadano Y, Fujita T.

Catheter Cardiovasc Interv. 2025 Aug 24. doi: 10.1002/ccd.70102.

The Endovascular Therapy Using Excimer Laser Atherectomy for Complex Femoropopliteal In-Stent Restenosis Lesions.

Horie K, Takahara M, Takiuchi S, Okamoto S, Yoshioka N, Kaneko N, Ogata K, Shintani Y, Haraguchi T, Ikeoka K, Kobayashi T, Suzuki K, Fukai K, Shima Y, Iiya M, Tada N, Iida O.

J Endovasc Ther. 2025 Aug 20:15266028251363466. doi: 10.1177/15266028251363466.

Impact of Peridevice Leak on Clinical Outcomes After Left Atrial Appendage Closure: The OCEAN-LAAC Registry.

Saito T, Tsuruta H, Kajino A, Iwata J, Sakata S, Ryuzaki T, Sago M, Tanaka S, Chatani R, Hachinohe D, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Ueno H, Kubo S, Shirai S, Nakashima M, Asami M, Yamamoto M, Ieda M, Hayashida K; OCEAN‐LAAC investigators.

J Am Heart Assoc. 2025 Aug 19;14(16):e044422. doi: 10.1161/JAHA.125.044422.

Clinical Impact of Early Changes in Serum Albumin on Patient Prognosis After Mitral-Transcatheter Edge-to-Edge Repair.

Shibata K, Yamamoto M, Kagase A, Tokuda T, Tsunamoto H, Shimura T, Kurita A, Yamaguchi R, Saji M, Izumi Y, Asami M, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bota H, Ohno Y, Yamawaki M, Hachinohe D, Ueno H, Nakazawa G, Otsuka T, Kubo S, Hayashida K; OCEAN‐Mitral Investigators.

J Am Heart Assoc. 2025 Aug 5;14(15):e041961. doi: 10.1161/JAHA.125.041961.

Plasma volume status predicting clinical outcomes in patients undergoing transcatheter edge-to-edge mitral valve repair.

Kagase A, Yamamoto M, Tokuda T, Kawahata R, Nishio H, Shimura T, Yamaguchi R, Sago M, Izumi Y, Saji M, Asami M, Enta Y, Nakashima M, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bouta H, Ohno Y, Yamawaki M, Ueno H, Mizutani K, Hachinohe D, Otsuka T, Kubo S, Hayashida K; OCEAN‐Mitral Investigators.

ESC Heart Fail. 2025 Aug;12(4):2855-2865. doi: 10.1002/ehf2.15295.

Tenting Sign on Intravascular Ultrasound: A Red Flag for Coronary Perforation Risk During Rotational Atherectomy.

Fu HN, Kuramitsu S, Tsao TP, Fujita T.

Catheter Cardiovasc Interv. 2025 Aug;106(2):974-977. doi: 10.1002/ccd.31650.

Minimalistic chronic total occlusion treatments using tip detection-antegrade dissection and re-entry: a case series.

Tadano Y, Eka Putra B, Sugie T, Kuramitsu S, Kaneko U, Kanno D, Fujita T.

Eur Heart J Case Rep. 2025 Jul 24;9(8):ytaf355. doi: 10.1093/ehjcr/ytaf355.

Successful Ethanol Infusion of Vein of Marshall With Bridge Collateral Using the Double-Balloon Technique Incorporating a Wedged Berman Catheter.

Kasai Y, Kitai T, Morita J, Murakami K, Fujita T.

J Arrhythm. 2025 Jul 22;41(4):e70152. doi: 10.1002/joa3.70152.

Outcomes of Lesions With Discordance Between FFR and Nonhyperemic Pressure Ratios.

Ha ET, Nishi T, Takahashi T, Yamazaki T, Saito Y, Kuramitsu S, Kawase Y, Parikh MA, Waksman R, Kobayashi Y.

JACC Cardiovasc Interv. 2025 Jul 14;18(13):1631-1642. doi: 10.1016/j.jcin.2025.05.032.

Transcatheter edge-to-edge repair vs medical therapy in atrial functional mitral regurgitation: a propensity score-based comparison from the OCEAN-Mitral and REVEAL-AFMR registries.

Kaneko T, Kagiyama N, Okazaki S, Amano M, Sato Y, Ohno Y, Obokata M, Sato K, Morita K, Kubo S, Izumi Y, Asami M, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Otsuki H, Naganuma T, Bota H, Yamawaki M, Ueno H, Nakazawa G, Hachinohe D, Otsuka T, Saji M, Yamamoto M, Hayashida K.

Eur Heart J. 2025 Jul 9:ehaf511. doi: 10.1093/eurheartj/ehaf511.

Intra- versus supra-annular self-expanding transcatheter heart valves in small aortic annuli.

Yamamoto M, Ryuzaki T, Hioki H, Kagase A, Shirai S, Ohno Y, Yashima F, Naganuma T, Yamawaki M, Watanabe Y, Yamanaka F, Mizutani K, Noguchi M, Izumo M, Takagi K, Asami M, Ueno H, Nishina H, Suzuyama H, Yamasaki K, Nishioka K, Hachinohe D, Fuku Y, Otsuka T, Hayashida K, Ocean-Tavi Investigators OBOT.

EuroIntervention. 2025 Jul 7;21(13):e749-e757. doi: 10.4244/EIJ-D-24-00966.

SAPIEN3 Ultra RESILIA versus NAVITOR valve system in patients with a small aortic annulus: Insights from the OCEAN-TAVI Registry.

Mizutani K, Yamamoto M, Hioki H, Kagase A, Shimura T, Nakazawa G, Hachinohe D, Ohno Y, Yashima F, Naganuma T, Shirai S, Yamanaka F, Noguchi M, Izumo M, Asami M, Ueno H, Nishina H, Ryusaki T, Otsuka T, Suzuyama H, Yamasaki K, Nishioka K, Fuku Y, Watanabe Y, Hayashida K.

Cardiovasc Revasc Med. 2025 Jul 1:S1553-8389(25)00350-1. doi: 10.1016/j.carrev.2025.06.036.

Transfemoral transcatheter aortic valve-in-valve implantation using endoconduit in a patient with right-sided aortic arch and complex vascular anatomy: a case report.

Otake R, Mizutani K, Horita R, Kaneko U, Hachinohe D.

Eur Heart J Case Rep. 2025 Jun 30;9(7):ytaf315. doi: 10.1093/ehjcr/ytaf315.

Positional Changes in Right Atrial Pressure Before and After PFO Closure in Platypnea-Orthodeoxia Syndrome.

Shitan H, Hachinohe D, Otake R, Horita R, Kaneko U, Kobayashi K, Fujita T.

JACC Case Rep. 2025 Jun 18;30(15):103767. doi: 10.1016/j.jaccas.2025.103767.

Hemolytic Anemia Following SAPIEN 3 Ultra RESILIA Implantation (from the OCEAN-TAVI Registry).

Ishizu K, Shirai S, Hayashi M, Morofuji T, Isotani A, Ohno N, Kakumoto S, Ando K, Yashima F, Nishina H, Izumo M, Asami M, Tada N, Yamawaki M, Naganuma T, Yamanaka F, Ohno Y, Ueno H, Noguchi M, Mizutani K, Takagi K, Suzuyama H, Yamasaki K, Nishioka K, Hachinohe D, Fuku Y, Otsuka T, Watanabe Y, Yamamoto M, Hayashida K; OCEAN-TAVI Investigators.

Am J Cardiol. 2025 Jun 15;245:71-80. doi: 10.1016/j.amjcard.2025.02.036.

Intraplaque Contrast Staining Confirmation by Real-Time Intravascular Ultrasound: A Success Key in Hydrodynamic Contrast Recanalization.

Sugie T, Kuramitsu S, Fu HN, Shimizu T, Matsuna N, Yui H, Tadano Y, Kaneko U, Kanno D, Kashima Y, Fujita T.

JACC Cardiovasc Interv. 2025 Jun 9;18(11):1473-1476. doi: 10.1016/j.jcin.2025.02.029.

Early rupture of a tetrafluoroethylene loop due to fixation with polypropylene resulting in recurrent mitral valve regurgitation; a word of caution.

Mitsube K, Wakabayashi N, Tsutsui M, Ushioda R, Kamiya H, Fujita T.

J Surg Case Rep. 2025 Jun 8;2025(6):rjaf393. doi: 10.1093/jscr/rjaf393.

Balloon-Assisted Subintimal Entry-Facilitated Tip Detection-Antegrade Dissection Reentry Technique: A Novel Antegrade Approach for Chronic Total Occlusion.

Rejeki VG, Tadano Y, Fujita T, Kuramitsu S.

Catheter Cardiovasc Interv. 2025 Jun;105(7):1664-1667. doi: 10.1002/ccd.31506.

Fracture of Rotational Atherectomy Burr: Pre-Fracture Signs, Mechanisms, and Management Strategies.

Kaneko U, Kashima Y, Sugie T, Kuramitsu S, Tadano Y, Takeuchi T, Kobayashi K, Kanno D, Fujita T.

Catheter Cardiovasc Interv. 2025 Jun;105(7):1608-1615. doi: 10.1002/ccd.31496.

Complete versus incomplete revascularization in patients with a non-ST-elevation myocardial infarction: Analysis from the e-ULTIMASTER registry.

Jiménez Díaz VA, Routledge H, Malik FT, Hildick-Smith D, Guédès A, Baello P, Kuramitsu S, Das R, Dewilde W, Portales JF, Angioi M, Smits PC, Romo AI.

Cardiovasc Revasc Med. 2025 Jun;75:25-30. doi: 10.1016/j.carrev.2024.07.011.

Unusual "crosstalk" phenomenon between right pulmonary veins observed during cryoballoon ablation.

Kasai Y, Kitai T, Morita J, Fujita T.

Indian Pacing Electrophysiol J. 2025 May-Jun;25(3):159-161. doi: 10.1016/j.ipej.2025.04.001.

Landiolol-Induced Severe Vasospastic Angina Leading to Total Coronary Occlusion During Coronary Computed Tomography Angiography.

Shimizu T, Hachinohe D, Kashima Y, Fujita T, Kuramitsu S.

Circ Rep. 2025 Mar 4;7(5):391-392. doi: 10.1253/circrep.CR-25-0016.

The First Experience of Transjugular Transcatheter Tricuspid Valve Replacement With LuX-Valve Plus System in Japan.

Horita R, Hachinohe D, Otake R, Sagar S, Shitan H, Mizutani K.

Circ Rep. 2025 Mar 13;7(5):393-394. doi: 10.1253/circrep.CR-25-0020.

Impact of Hospital Volume on Procedural Failure of Endovascular Treatment for Acute Limb Ischemia: The Japanese Nationwide Endovascular Therapy Registry.

Haraguchi T, Takahara M, Iida O, Kohsaka S, Ishii H, Nakamura M, Amano T, Fujita T, Kozuma K.

Angiology. 2025 Apr 25:33197251333872. doi: 10.1177/00033197251333872.

Delayed Left Ventricular Rupture After Radiofrequency Catheter Ablation of Premature Ventricular Contractions Triggering Ventricular Fibrillation.

Kasai Y, Kitai T, Morita J, Horita R, Kasai J, Fujita T.

CJC Open. 2025 Apr 24;7(7):952-954. doi: 10.1016/j.cjco.2025.04.013.

Tricuspid regurgitation and outcomes in mitral valve transcatheter edge-to-edge repair.

Matsumoto S, Ohno Y, Noda S, Miyamoto J, Kamioka N, Murakami T, Ikari Y, Kubo S, Izumi Y, Saji M, Yamamoto M, Asami M, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bota H, Yamawaki M, Ueno H, Mizutani K, Hachinohe D, Otsuka T, Hayashida K.

Eur Heart J. 2025 Apr 15;46(15):1415-1427. doi: 10.1093/eurheartj/ehae924.

Snare-assisted delivery and coaxial optimization of a self-expanding transcatheter aortic valve in the horizontal aorta.

Kaneko U, Hachinohe D, Horita R, Kobayashi K.

Eur Heart J Case Rep. 2025 Apr 5;9(5):ytaf159. doi: 10.1093/ehjcr/ytaf159.

Geriatric Nutritional Risk Index Assessment in Patients Undergoing Transcatheter Edge-to-Edge Repair.

Shibata K, Yamamoto M, Kagase A, Tokuda T, Tsunamoto H, Shimura T, Kurita A, Yamaguchi R, Saji M, Asami M, Enta Y, Nakashima M, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bota H, Ohno Y, Yamawaki M, Hachinohe D, Ueno H, Mizutani K, Otsuka T, Kubo S, Hayashida K; OCEAN-Mitral Investigators.

JACC Adv. 2025 Apr;4(4):101631. doi: 10.1016/j.jacadv.2025.101631.

3D printing-enhanced transcatheter closure of residual shunts post-ventricular septal perforation: multimodal imaging's crucial role.

Hachinohe D, Hara H, Makino K, Horita R, Shitan H, Mitsube K.

Cardiovasc Interv Ther. 2025 Apr;40(2):457-458. doi: 10.1007/s12928-024-01064-8.

Transcatheter mitral valve replacement in failed surgical annuloplasty ring with Impella support.

Hachinohe D, Horita R, Sagar S, Ohtake R, Shitan H, Mizutani K.

Cardiovasc Interv Ther. 2025 Apr;40(2):443-444. doi: 10.1007/s12928-024-01068-4.

Impact of Transcatheter Edge-to-Edge Repair in Patients With Cardiac Sarcoidosis: Insights From the OCEAN-Mitral Registry.

Hiruma T, Saji M, Nanasato M, Takamisawa I, Higuchi R, Izumi Y, Abe R, Isobe M, Yamamoto M, Kubo S, Asami M, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bota H, Ohno Y, Hachinohe D, Yamawaki M, Ueno H, Mizutani K, Otsuka T, Hayashida K; OCEAN‐Mitral Investigators.

J Am Heart Assoc. 2025 Apr;14(7):e039243. doi: 10.1161/JAHA.124.039243.

Detection and nanagement of stent under-expansion in self-expanding TAVR using a steep right anterior oblique view.

Kaneko U, Hachinohe D, Horita R, Otake R, Mizutani K, Kobayashi K.

Cardiovasc Interv Ther. 2025 Apr;40(2):438-440. doi: 10.1007/s12928-024-01078-2.

Pulmonary vein isolation through a residual shunt after direct closure of sinus venosus atrial septal defect with severe inferior vena cava tortuosity due to scoliosis.

Kasai Y, Kitai T, Horita R, Otake R, Morita J, Hachinohe D.

HeartRhythm Case Rep. 2025 Mar 28;11(6):563-566. doi: 10.1016/j.hrcr.2025.03.019.

Cryoablation as an alternative strategy for bidirectional cavotricuspid isthmus block following multiple failed sessions of radiofrequency ablation due to epicardial-endocardial breakthrough: A case report.

Kasai Y, Kitai T, Morita J, Fujita T.

Indian Pacing Electrophysiol J. 2025 Mar-Apr;25(2):118-121. doi: 10.1016/j.ipej.2025.02.004.

PseuSeal technique: endovascular repair of Iatrogenic pseudoaneurysm using ExoSeal.

Haraguchi T, Kasai Y, Tsujimoto M, Kashima Y, Sato K, Fujita T.

CVIR Endovasc. 2025 Mar 17;8(1):21. doi: 10.1186/s42155-025-00536-z.

Long-Term Outcomes of True Versus Nontrue Coronary Bifurcation Lesions Treated With Bioresorbable Polymer Sirolimus-Eluting Ultimaster Stent Under Intravascular Imaging Guidance.

Matsuna N, Kuramitsu S, Tadano Y, Sugie T, Kaneko U, Yui H, Shimizu T, Miura S, Kobayashi K, Kanno D, Kashima Y, Fujita T.

Am J Cardiol. 2025 Mar 15;239:57-63. doi: 10.1016/j.amjcard.2024.12.025.

Prevalence and Clinical Outcomes of Discordant Lesions Between Fractional Flow Reserve and Nonhyperemic Pressure Ratios in Clinical Practice: The J-PRIDE Registry.

Kuramitsu S, Kawase Y, Shinozaki T, Domei T, Yamanaka F, Kaneko U, Kakuta T, Horie K, Terai H, Ando H, Shiono Y, Tagashira T, Nogi K, Kubo T, Asano T, Shiraishi J, Otake H, Sugano A, Anai R, Iwai A, Kikuta Y, Nishina H, Fujita T, Amano T, Iwabuchi M, Yokoi H, Akasaka T, Matsuo H, Tanaka N; J-PRIDE Investigators.

Circulation. 2025 Mar 11;151(10):672-685. doi: 10.1161/CIRCULATIONAHA.124.071139.

Cutting balloon versus standard balloon for lesion preparation of drug-coated balloon treatment in de-novo coronary artery lesions: Rationale and Design of the Randomized NATURE trial.

Ono M, Asano T, Noguchi M, Kogame N, Iijima R, Osakada K, Ando K, Ishihara T, Nishida K, Nanasato M, Tanabe K, Muramatsu T, Okamura A, Kinoshita Y, Hibi K, Suwa S, Kuriyama N, Okada K, Nakazawa G, Ashikaga T, Tadano Y, Shiomi H, Nakamura M, Miyazawa A, Miyata S, Uno K, Kadota K, Kozuma K; NATURE trial investigators.

Cardiovasc Revasc Med. 2025 Mar 8:S1553-8389(25)00102-2. doi: 10.1016/j.carrev.2025.03.009.

The DELIVER Technique: Deep Engagement of Guide or ChiLd-guIde Catheter for Burr DeliVEry and Rotational Atherectomy.

Kaneko U, Kashima Y, Kuramitsu S, Tadano Y, Sugie T, Kobayashi K, Kanno D, Sato K, Fujita T.

JACC Case Rep. 2025 Mar 5;30(5):103177. doi: 10.1016/j.jaccas.2024.103177.

Successful radiofrequency ablation via transseptal approach for premature ventricular contractions originating from left ventricular outflow tract following self-expanding transcatheter aortic valve implantation.

Kasai Y, Kitai T, Horita R, Morita J, Hachinohe D.

J Arrhythm. 2025 Feb 13;41(1):e70025. doi: 10.1002/joa3.70025.

Impact of Angiographically Detected Residual Trabeculation After Left Atrial Appendage Closure Using the WATCHMAN Device: Insight From the OCEAN-LAAC Registry.

Chatani R, Kubo S, Nishiura N, Mushiake K, Ono S, Maruo T, Kadota K, Sago M, Tanaka S, Asami M, Hachinohe D, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Ueno H, Shirai S, Nakashima M, Yamamoto M, Hayashida K; OCEAN‐LAAC investigators.

J Cardiovasc Electrophysiol. 2025 Feb;36(2):347-358. doi: 10.1111/jce.16517.

P-Wave Oversensing by the Implantable Cardiac Monitor During Paroxysmal Atrioventricular Block: What Is the Mechanism?

Kasai Y, Morita J, Kitai T, Iitsuka K, Munakata Y, Kasai J, Fujita T.

J Cardiovasc Electrophysiol. 2025 Feb;36(2):512-516. doi: 10.1111/jce.16550.

Handgrip strength as a marker of frailty in patients with transcatheter edge-to-edge repair: Insights from the OCEAN-mitral registry.

Saji M, Nanasato M, Takamisawa I, Higuchi R, Izumi Y, Iwakura T, Isobe M, Ikeda T, Yamamoto M, Kubo S, Asami M, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Yamaguchi J, Naganuma T, Bota H, Ohno Y, Hachinohe D, Yamawaki M, Ueno H, Mizutani K, Otsuka T, Hayashida K; OCEAN-Mitral investigators.

Int J Cardiol. 2025 Feb 1;420:132743. doi: 10.1016/j.ijcard.2024.132743.

Comparative durability of pacemaker leads in transvenous lead extraction: An evaluation through bench testing.

Morita J, Okada A, Kusumoto F, Nakamura K.

Heart Rhythm O2. 2025 Jan 30;6(4):481-488. doi: 10.1016/j.hroo.2025.01.015.

Two distinct stages and mechanisms of ST-elevation during cryothermal cavotricuspid isthmus ablation guided by intracardiac echocardiography: A case report.

Kasai Y, Iitsuka K, Morita J, Kitai T.

Indian Pacing Electrophysiol J. 2025 Jan-Feb;25(1):32-36. doi: 10.1016/j.ipej.2024.10.002.

Outcomes of Left Atrial Appendage Closure in Hemodialysis Patients With Atrial Fibrillation: The OCEAN-LAAC Registry.

Tanaka S, Imamura T, Fukuda N, Ueno H, Kinugawa K, Sago M, Chatani R, Hachinohe D, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Kubo S, Shirai S, Nakashima M, Asami M, Yamamoto M, Hayashida K; OCEAN-LAAC Investigators.

JACC Asia. 2025 Jan 21;5(1):174-186. doi: 10.1016/j.jacasi.2024.10.022.

DOAC Score for Predicting Clinical Outcomes After Left Atrial Appendage Closure.

Asami M, Horiuchi Y, Tanaka J, Yoshiura D, Taniwaki M, Komiyama K, Yuzawa H, Tanabe K, Sago M, Tanaka S, Chatani R, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Hachinohe D, Ueno H, Kubo S, Shirai S, Nakashima M, Yamamoto M, Hayashida K; OCEAN-LAAC investigators.

CJC Open. 2025 Jan 17;7(4):420-428. doi: 10.1016/j.cjco.2025.01.009.

Initial Findings Concerning the Latest Self-Expandable Evolut FX Valve: A Report Using OCEAN-TAVI Registry Data.

Yashima F, Yamamoto M, Shirai S, Tada N, Naganuma T, Yamawaki M, Yamanaka F, Mizutani K, Noguchi M, Ueno H, Takagi K, Ohno Y, Izumo M, Nishina H, Suzuyama H, Yamasaki K, Nishioka K, Hachinohe D, Fuku Y, Otsuka T, Asami M, Watanabe Y, Hayashida K; OCEAN-TAVI investigators.

Am J Cardiol. 2025 Jan 15;235:59-66. doi: 10.1016/j.amjcard.2024.10.015.

Importance of Successful Revascularization in Acute Limb Ischemia: Sub-Analysis From the RESCUE ALI Trial.

Haraguchi T, Tan M, Uchida D, Dannoura Y, Shibata T, Iwata S, Azuma N.

Catheter Cardiovasc Interv. 2025 Jan;105(1):211-218. doi: 10.1002/ccd.31319.

-　2024　-

The influence between plaque rupture and non-plaque rupture on clinical outcomes in patients with ST-segment elevation myocardial infarction after primary percutaneous coronary intervention: a prospective cohort study.

Yang X, Yang J, Kashima Y, Hachinohe D, Sugie T, Xu S, Guo X, Li X, Hu X, Sun B, Nagraj S, Lymperopoulos A, Kim YH, Tu S, Dong H.

J Thorac Dis. 2024 Nov 30;16(11):7771-7786. doi: 10.21037/jtd-24-1482.

Valve Performance Between Latest-Generation Balloon-Expandable and Self-Expandable Transcatheter Heart Valves in a Small Aortic Annulus.

Hioki H, Yamamoto M, Shirai S, Ohno Y, Yashima F, Naganuma T, Yamawaki M, Watanabe Y, Yamanaka F, Mizutani K, Ryuzaki T, Noguchi M, Izumo M, Takagi K, Asami M, Ueno H, Nishina H, Otsuka T, Suzuyama H, Yamasaki K, Nishioka K, Hachinohe D, Fuku Y, Hayashida K; OCEAN-TAVI Investigators.

JACC Cardiovasc Interv. 2024 Nov 25;17(22):2612-2622. doi: 10.1016/j.jcin.2024.08.049.

En-Face View for Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Coronary Artery Obstruction.

Hachinohe D, Tada N, Horita R, Shitan H.

Circ J. 2024 Nov 25;88(12):2021. doi: 10.1253/circj.CJ-24-0670. Epub 2024 Oct 9.

In-hospital initiation of angiotensin receptor-neprilysin inhibition in acute heart failure: the PREMIER trial.

Tanaka A, Kida K, Matsue Y, Imai T, Suwa S, Taguchi I, Hisauchi I, Teragawa H, Yazaki Y, Moroi M, Ohashi K, Nagatomo D, Kubota T, Ijichi T, Ikari Y, Yonezu K, Takahashi N, Toyoda S, Toshida T, Suzuki H, Minamino T, Nogi K, Shiina K, Horiuchi Y, Tanabe K, Hachinohe D, Kiuchi S, Kusunose K, Shimabukuro M, Node K.

Eur Heart J. 2024 Nov 8;45(42):4482-4493. doi: 10.1093/eurheartj/ehae561.

Anatomical vs. electrophysiological approach for ablation of premature ventricular contractions originating from the left ventricular summit (ISESHIMA-SUMMIT Study).

Watanabe R, Nagashima K, Shirai Y, Kitai T, Okada T, Tokuda M, Fukunaga M, Onuki K, Nakatani Y, Yoshimura S, Takatsuki S, Hashimoto K, Yamashita S, Kato M, Uchida F, Fukamizu S, Hojo R, Mori H, Matsumoto K, Kato H, Suga K, Sakurai T, Sakamoto Y, Hayashi T, Wakamatsu Y, Hirata S, Hirata M, Sawada M, Kurokawa S, Okumura Y.

Europace. 2024 Nov 1;26(11):euae278. doi: 10.1093/europace/euae278.

The "bow and backbend" technique with a balloon lever for challenging right inferior pulmonary vein isolation in cryoballoon ablation.

Kasai Y, Iitsuka K, Morita J, Kitai T.

Indian Pacing Electrophysiol J. 2024 Nov-Dec;24(6):370-372. doi: 10.1016/j.ipej.2024.09.010.

Efficacy and safety of the needle rendezvous technique for infrainguinal arterial calcified lesions.

Haraguchi T, Tsujimoto M, Kashima Y, Kasai Y, Sato K, Fujita T.

CVIR Endovasc. 2024 Oct 29;7(1):77. doi: 10.1186/s42155-024-00490-2.

Side branch preservation using tip detection-antegrade dissection re-entry after failed subintimal tracking and re-entry in chronic total occlusion: a case report.

Dwiputra B, Tadano Y, Sugie T, Fujita T.

Eur Heart J Case Rep. 2024 Oct 22;8(11):ytae571. doi: 10.1093/ehjcr/ytae571.

Correlations Between Plasma BNP Level and Risk of Thrombotic-Hemorrhagic Events After Left Atrial Appendage Closure.

Imamura T, Kataoka N, Tanaka S, Ueno H, Kinugawa K, Nakashima M, Yamamoto M, Sago M, Chatani R, Asami M, Hachinohe D, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Kubo S, Shirai S, Hayashida K; OCEAN-LAAC Investigators.

J Clin Med. 2024 Oct 18;13(20):6232. doi: 10.3390/jcm13206232.

Can Intravascular Lithotripsy Compress Noneruptive Calcified Nodules?

Huang WC, Kuramitsu S, Kanno D, Kashima Y, Lu TM, Fujita T.

JACC Cardiovasc Interv. 2024 Oct 14;17(19):2307-2308. doi: 10.1016/j.jcin.2024.06.026.

Efficacy of TAV-in-TAV using SAPIEN3 Ultra RESILIA for supra-skirtal-leakage with intravascular hemolysis.

Otake R, Hachinohe D, Horita R, Armando Diaz J, Shitan H, Fujita T.

Cardiovasc Interv Ther. 2024 Oct;39(4):507-508. doi: 10.1007/s12928-024-01007-3.

Real-time Ripple technique: A case report on Ripple map for real-time identification of conduction gaps without first-pass pulmonary vein isolation.

Okada T, Kasai Y, Kitai T, Fujita T.

Indian Pacing Electrophysiol J. 2024 Sep-Oct;24(5):291-294. doi: 10.1016/j.ipej.2024.06.008.

Bailout subintimal trans-catheter withdrawal (STRAW) technique for a distally extended coronary hematoma.

Tadano Y, Sugie T, Kanno D, Fujita T.

Catheter Cardiovasc Interv. 2024 Sep;104(3):516-520. doi: 10.1002/ccd.31160.

Clinical outcomes of acute limb ischaemia caused by femoropopliteal stent thrombosis.

Nakao S, Iida O, Takahara M, Suematsu N, Yamaoka T, Matsuda D, Nakama T, Fujihara M, Tobita K, Koyama E, Haraguchi T, Ogata K, Mano T.

EuroIntervention. 2024 Sep 16;20(18):e1163-e1172. doi: 10.4244/EIJ-D-24-00016.

Successful endovascular therapy with "Direct tip injection in occlusive lesions (DIOL)" fashion for persistent sciatic artery aneurysmal occlusion: A case report.

Tsujimoto M, Haraguchi T, Kashima Y, Sato K, Fujita T.

J Cardiol Cases. 2024 Sep 12;30(6):185-188. doi: 10.1016/j.jccase.2024.08.006.

Tip detection-antegrade dissection and re-entry (TD-ADR) with integrated fluoroscopic and intravascular ultrasound images in chronic total occlusion: first case report of integrated TD-ADR technique.

Tadano Y, Kuramitsu S, Sugie T, Kanno D, Fujita T.

Eur Heart J Case Rep. 2024 Aug 14;8(8):ytae378. doi: 10.1093/ehjcr/ytae378.

Tip-detection antegrade dissection and re-entry into a seriously collapsed true lumen.

Tadano Y, Sugie T, Kanno D, Fujita T.

Eur Heart J Case Rep. 2024 Aug 14;8(8):ytae373. doi: 10.1093/ehjcr/ytae373.

Steep right anterior oblique view of self-expandable transcatheter aortic valve to timely detect stent under-expansion or non-uniform expansion before final release: a case series.

Kaneko U, Hachinohe D, Kobayashi K, Shitan H, Horita R, Ootake R, Fujita T.

Eur Heart J Case Rep. 2024 Aug 7;8(8):ytae405. doi: 10.1093/ehjcr/ytae405.

Severe intraprosthetic aortic insufficiency immediately after implantation of a SAPIEN 3 Ultra RESILIA valve with spontaneous resolution: case report.

Diaz JA, Kobayashi K, Hachinohe D, Horita R, Shitan H.

Eur Heart J Case Rep. 2024 Aug 6;8(8):ytae402. doi: 10.1093/ehjcr/ytae402.

Cryoballoon ablation using the sheath-in-sheath technique in a patient with a tortuous common iliac vein.

Kasai Y, Kitai T, Morita J, Iitsuka K, Haraguchi T, Tsujimoto M, Okada T, Munakata Y, Kasai J, Fujita T.

Clin Case Rep. 2024 Aug 3;12(8):e9257. doi: 10.1002/ccr3.9257.

Impact of Antiplatelet Therapy on 5-Year Outcomes After Fractional Flow Reserve-Guided Deferral of Revascularization in Nonsignificant Obstructive Coronary Artery Disease.

Kurita T, Kuramitsu S, Ishii M, Takasaki A, Domei T, Matsuo H, Horie K, Ando H, Terai H, Kikuta Y, Ishihara T, Saigusa T, Sakamoto T, Suematsu N, Shiono Y, Asano T, Tsujita K, Masamura K, Doijiri T, Toyota F, Ogita M, Shiraishi J, Harada K, Isogai H, Anai R, Sonoda S, Yokoi H, Tanaka N, Dohi K; J-CONFIRM Investigators.

Circ Rep. 2024 Jul 20;6(8):313-321. doi: 10.1253/circrep.CR-24-0069.

Intracardiac Echocardiography-Guided Transseptal Puncture Invisible by Transesophageal Echocardiography After Secundum Atrial Septal Defect Closure.

Kasai Y, Kitai T, Horita R, Hachinohe D, Morita J, Otake R, Shitan H, Munakata Y, Kasai J, Fujita T.

CJC Open. 2024 Jul 14;6(10):1207-1209. doi: 10.1016/j.cjco.2024.07.002.

Acute leaflet malfunction of Navitor valve with severe intraprosthetic aortic insufficiency immediately after implantation.

Horita R, Hachinohe D, Otake R, Diaz JA, Shitan H, Fujita T.

Cardiovasc Interv Ther. 2024 Jul;39(3):331-332. doi: 10.1007/s12928-024-00995-6.

Comparative Data of Procedural and Midterm Outcomes in Patients Who Underwent Percutaneous Left Atrial Appendage Closure Between the WATCHMAN FLX and WATCHMAN 2.5 Devices　- Insight From the OCEAN-LAAC Registry.

Nakashima M, Yamamoto M, Sago M, Tanaka S, Chatani R, Asami M, Hachinohe D, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Ueno H, Kubo S, Shirai S, Hayashida K; OCEAN-LAAC Investigators.

Circ J. 2024 Jun 25;88(7):1187-1197. doi: 10.1253/circj.CJ-24-0062.

The Clinical Course of Fast-Growing Myxoma　- Echocardiography and Computed Tomography Observation.

Horita R, Hashimoto M, Kasai Y, Otake R, Shitan H, Hachinohe D, Fujita T.

Circ J. 2024 Jun 25;88(7):1199. doi: 10.1253/circj.CJ-24-0006.

Dual-chamber pacing with closed-loop stimulation in a sleep syncope case.

Morita J, Kasai Y, Kitai T, Fujita T, Kondo Y.

HeartRhythm Case Rep. 2024 Jun 22;10(9):664-667. doi: 10.1016/j.hrcr.2024.06.015.

Prognostic impact of increase in left atrial volume following left atrial appendage closure: Insights from the OCEAN-LAAC registry.

Nonaka H, Asami M, Horiuchi Y, Tanaka J, Yoshiura D, Komiyama K, Yuzawa H, Tanabe K, Sago M, Tanaka S, Chatani R, Hachinohe D, Naganuma T, Ohno Y, Tani T, Okamatsu H, Mizutani K, Watanabe Y, Izumo M, Saji M, Mizuno S, Ueno H, Kubo S, Shirai S, Nakashima M, Yamamoto M, Hayashida K; OCEAN-LAAC investigators.

Int J Cardiol Heart Vasc. 2024 Jun 21;53:101449. doi: 10.1016/j.ijcha.2024.101449.

Initial Results of Intra-Annular Self-Expandable Valves: Insights From the OCEAN-TAVI Registry.

Shirai S, Yamamoto M, Yashima F, Hioki H, Ryuzaki T, Morofuji T, Naganuma T, Yamanaka F, Mizutani K, Noguchi M, Ueno H, Takagi K, Ohno Y, Izumo M, Nishina H, Suzuyama H, Yamasaki K, Hachinohe D, Fuku Y, Otsuka T, Asami M, Watanabe Y, Hayashida K; OCEAN-TAVI Investigators.

JACC Asia. 2024 Jun 11;4(7):536-544. doi: 10.1016/j.jacasi.2024.04.010.

Successful coronary sinus left ventricular lead extraction 9 years postimplantation using the wire ThRoUgh Snare Twice (wire TRUST) technique.

Kasai Y, Morita J, Haraguchi T, Kitai T, Okada T, Suzuki K, Yamazaki R, Munakata Y, Kasai J, Fujita T.

Clin Case Rep. 2024 Jun 4;12(6):e9039. doi: 10.1002/ccr3.9039.

Retrieval of the Aveir™ leadless pacemaker with the double-snare technique.

Morita J, Kondo Y, Kasai Y, Kitai T.

Eur Heart J Case Rep. 2024 May 30;8(6):ytae267. doi: 10.1093/ehjcr/ytae267.

Where Has an IVUS Outer Sheath Gone?

Shimizu T, Kuramitsu S, Otake R, Kanno D, Kashima Y, Fujita T.

JACC Cardiovasc Interv. 2024 May 27;17(10):1283-1284. doi: 10.1016/j.jcin.2024.02.021.

Where have the microbubbles come from ? Left inferior pulmonary arteriovenous fistula detected by transoesophageal echocardiography.

Horita R, Hachinohe D, Kasai Y, Otake R, Shitan H, Fujita T.

Eur Heart J Imaging Methods Pract. 2024 May 24;2(1):qyae052. doi: 10.1093/ehjimp/qyae052.

Quantitative flow ratio versus fractional flow reserve for Heart Team decision-making in multivessel disease: the randomised, multicentre DECISION QFR trial.

Asano T, Tanigaki T, Hoshino M, Yasunaga M, Nonaka H, Emori H, Katagiri Y, Miyazaki Y, Sotomi Y, Kogame N, Kuramitsu S, Saito A, Miyata K, Takaoka Y, Kanie T, Yamasaki M, Yoshino K, Wakabayashi N, Ouchi K, Kodama H, Shiina Y, Tamaki R, Nishihata Y, Masuda K, Suzuki T, Reiber JHC, Okamura T, Higuchi Y, Kakuta T, Misumi H, Abe K, Komiyama N, Tanabe K, Matsuo H, Qfr Investigators OBOTD.

EuroIntervention. 2024 May 10;20(9):561-570. doi: 10.4244/EIJ-D-23-00674.

Performance and outcomes of the SAPIEN 3 Ultra RESILIA transcatheter heart valve in the OCEAN-TAVI registry.

Yamamoto M, Yashima F, Shirai S, Tada N, Naganuma T, Yamawaki M, Yamanaka F, Mizutani K, Noguchi M, Ueno H, Takagi K, Ohno Y, Izumo M, Nishina H, Suzuyama H, Yamasaki K, Nishioka K, Hachinohe D, Fuku Y, Otsuka T, Asami M, Watanabe Y, Hayashida K, Ocean-Tavi Investigators OBOT.

EuroIntervention. 2024 May 10;20(9):579-590. doi: 10.4244/EIJ-D-23-00996.

Initial results of transcatheter modification of left atrial appendage by obliteration with device in patients with nonvalvular atrial fibrillation: Real-world data from the TERMINATOR registry.

Hara H, Kubo S, Nakajima Y, Matsumoto T, Kondo Y, Sugane H, Okubo K, Nakagawa K, Nagatomo D, Hachinohe D, Kusa S, Goya M, Nanasato M, Arita T, Yamasaki H, Kuwabara K, Yoshiyama T, Tanaka N, Masuda M, Sakamoto T, Nakashima M, Ohno Y, Saito S, Fukunaga M.

J Cardiol. 2024 May;83(5):298-305. doi: 10.1016/j.jjcc.2023.09.010.

Improvement in respiratory function and exercise tolerance following video-assisted thoracoscopic diaphragm plication for symptomatic iatrogenic persistent diaphragm paralysis after radiofrequency catheter ablation.

Kasai Y, Hase R, Kitai T, Morita J, Fujita T.

J Arrhythm. 2024 Apr 21;40(3):614-617. doi: 10.1002/joa3.13039.

Rendezvous-PIERCE technique: establishing a channel through severe calcification in infrainguinal arterial lesions using needle rendezvous.

Haraguchi T, Tsujimoto M, Kashima Y, Sato K, Fujita T.

CVIR Endovasc. 2024 Mar 15;7(1):29. doi: 10.1186/s42155-024-00445-7.

Silent steam pop detected by transesophageal echocardiography for premature ventricular contractions originating from the aortomitral continuity.

Kasai Y, Kasai J, Kitai T, Horita R, Morita J, Fujita T.

J Echocardiogr. 2024 Mar;22(1):61-62. doi: 10.1007/s12574-023-00602-2.

Repeat drug-coated balloon angioplasty for femoropopliteal lesions: 12-month results from a retrospective observational study.

Haraguchi T, Tsujimoto M, Kashima Y, Sato K, Fujita T.

CVIR Endovasc. 2024 Feb 29;7(1):24. doi: 10.1186/s42155-024-00434-w.

Successful implantation of a left ventricular lead for cardiac resynchronization therapy upgrade via an occluded subclavian vein using the balloon-target puncture technique.

Kasai Y, Morita J, Haraguchi T, Kitai T.

Eur Heart J Case Rep. 2024 Feb 23;8(3):ytae110. doi: 10.1093/ehjcr/ytae110.

One-Year Clinical Outcomes and Prognostic Factors Following Revascularization in Patients With Acute Limb Ischemia　- Results From the RESCUE ALI Study.

Tan M, Takahara M, Haraguchi T, Uchida D, Dannoura Y, Shibata T, Iwata S, Azuma N.

Circ J. 2024 Feb 22;88(3):331-338. doi: 10.1253/circj.CJ-23-0348.

Use of the Buddy Judkins Catheter and Stiff Wire Technique to Deliver Sheaths for Catheter Ablation Through Iliac Vein Tortuosity.

Kasai Y, Kitai T, Morita J, Okada T, Munakata Y, Kasai J, Fujita T.

CJC Open. 2024 Feb 18;6(5):725-727. doi: 10.1016/j.cjco.2024.01.014.

Sex Differences in 5-Year Outcomes After Deferral of Revascularization Following Physiological Coronary Assessment.

Ishihara T, Kuramitsu S, Matsuo H, Horie K, Takashima H, Terai H, Kikuta Y, Saigusa T, Sakamoto T, Suematsu N, Shiono Y, Asano T, Tsujita K, Masamura K, Doijiri T, Toyota F, Ogita M, Kurita T, Matsuo A, Harada K, Yaginuma K, Sonoda S, Yokoi H, Tanaka N, Mano T; J-CONFIRM Investigators.

Circ Rep. 2024 Jan 31;6(2):19-27. doi: 10.1253/circrep.CR-23-0100.

Outcomes of left bundle branch area pacing compared to His bundle pacing and right ventricular apical pacing in Japanese patients with bradycardia.

Kono H, Kuramitsu S, Fukunaga M, Korai K, Nagashima M, Hiroshima K, Ando K.

J Arrhythm. 2024 Jan 28;40(2):333-341. doi: 10.1002/joa3.12997.

Outcomes of non-flow-limiting spiral dissection after drug-coated balloon angioplasty for de novo femoropopliteal lesions.

Haraguchi T, Kuramitsu S, Tsujimoto M, Kashima Y, Sato K, Fujita T.

Catheter Cardiovasc Interv. 2024 Jan;103(1):97-105. doi: 10.1002/ccd.30911.

© 2025 札幌心臓血管クリニック　Recruit. Created with ❤ using WordPress and Kubio